This complication of tumours

This complication of tumours of a pituitary body in the beginning distinguished only at its greatest expression and considered as rather adverse prognostic sign. However now it was found out, that the hemorrhage in tumoral mass meets very often. In the softest form it can proceed asymptomatically or to be accompanied by a sudden headache hoodia gordonii of the different intensity which is passing in some days. The hemorrhage often accelerates tumour growth, that at it a locating leads to hypopituitarism development, and at - to acute disturbance of sight or full blindness. Result spontaneous treatment from tumours can be also. The factors defining growth of a tumour, are found out insufficiently. At rats tumour development is promoted by the big doses of estrogens, but till now there are no data about a role of estrogens in this process at the person. It is important to consider, however, that sometimes tumour growth is accelerated at pregnancy.
Pregnant women with signs of a tumour of a pituitary body in II and III trimester are exposed to the raised risk of development of symptoms of a prelum of a visual decussation. Whether it is bound to growth of a tumour or with normal augmentation of the sizes of a pituitary body - is obscure, as such symptoms usually spontaneously disappear after sorts. Nejrorentgenologichesky data Small percent (5-15) tumours of a pituitary body for the first time find out at the roentgenography of a skull spent with other purposes. On roentgenograms the enlarged or deformed Turkish saddle is visible. At patients the pituitary body tumour meets these radiological signs at which, the endocrine semiology is besides, shown, more often, than in 70 of cases. However in the absence of symptoms the most probable diagnosis is the syndrome of an "empty" Turkish saddle (see more low, and also tab. 7-7). Endocrinologic implications At patients endocrine symptoms happen to pituitary body tumours of two types: 1 - a hypofunction as a result of destruction of a healthy tissue , caused by pressure of a tumour or disturbance of portal blood supply and 2 - hyperfunction owing to a tumoral degeneration and-or a hyperplasia. Hyperfunction is caused first of all by the tumours producing a hormone of growth, Prolactinum and , but can characterise also TTG - and FsG-sekretnrujushchie tumours (see more low). Besides, can co-exist hyper-and a hypofunction that meets at a hypogonadism, secondary in relation to . Signs and symptoms of an endocrine hypofunction have been described in the previous section. There are the symptoms bound to a depression of function of sexual glands, and then - symptoms of insufficiency of function of adrenals and a thyroid gland more often. Deficiency of a hormone of growth on frequency occupies intermediate position, but gets clinical value only if develops before end of process of growth. Dysfunction of a back share of a pituitary body () at pituitary body adenomas meets rather seldom (while the tumour does not reach very big sizes), but at cranyopharyngiomas is observed often. DIAGNOSTIC METHODS The purpose of usually applied diagnostic methods are 1 – differentiation alli diet pill of tumours of a pituitary body from others disorders; 2 - definition of the sizes of a tumour and degree of destruction of a Turkish saddle and formations; 3 - finding-out of degree of deficiency of hormones. Some researches are besides, applied to exact definition of anatomic borders of a tumour and degree of shift of surrounding structures that is necessary for treatment planning development. The endocrinologic estimation of a hypofunction of a pituitary body is surveyed further in the present chapter, and also in chapter 9, and hyperfunction - in following section. Whenever possible the full endocrinologic estimation should be spent prior to the beginning of treatment as character and volume of medical actions depends on hypopituitarism degree. However in some circumstances it to make it is impossible, for example at the patient with quickly progressing depression of sight or against other progressing neurologic symptoms which demand an urgent surgical intervention. In such cases of the patient it is necessary to survey as suffering a panhypopituitarism and before diagnostic or medical procedure (for example, a pneumoencephalography and operation) it is necessary for it to enter steroids. Nejrorentgenologichesky researches Examples usually applied researches, and also character of the information received with their help are shown on 7-12. Skull roentgenography. In the beginning the patient with suspicion on a pituitary body tumour should make lateral and frontback roentgenography of a skull. Experts considerably disagree concerning the normal sizes, the form and thin features of osteal structure of a Turkish saddle on roentgenograms. In a usual lateral picture the maximum sizes of frontback diameter, i.e. The greatest distance from forward concavity of a Turkish saddle to a first line of its backrest, 17 mm, and the maximum depth do not exceed a fossa, i.e.