THE HORMONE Definition of initial

THE HORMONE Definition of initial level Definition of level in plasma allows to differentiate normal and its raised maintenance and consequently it is useful at differentiation of a primary and secondary hypothyrosis. Each laboratory should have results of own definitions of normal level both in an initial condition, and after pituitary body stimulation. The top border of fluctuations in norm at use of a standard preparation of comparison ( 68/38) reaches 6 mked/ml. Level rising find sometimes at children with a subthalamic hypothyrosis. In medrol dosepak case of rising of level which is not giving in to suppression by thyroid hormones, it is necessary to consider possibility of the artefact caused by cross-reacting antibodies to entered earlier bull . The lowered indicators it is impossible reliably from norm. assays Assay about Thyrotropinum-rilizing a hormone (TGR-TEST). A technique. Intravenously enter 500 mkg ; blood samples for definition take on 0, 15, 30, 60 and 120th minute after introduction . Not changed indicators. At women and men 40 years level aged are younger should raise not less than on 6 mked/ml, and at men aged is more senior 40 years - not less than on 2 mked/ml.
The maximum value are registered on 30th minute. Interpreting of results. Even at healthy faces reaction can be sometimes lowered, that complicates allocation of group of patients with partial insufficiency of reserve . At. A primary hypothyrosis reaction on is strengthened, whereas at a hyperthyroidism or at the patients receiving a thyroxine, , pharmacological doses of glucocorticoids, and also is frequent at euthyroid illness this reaction is absent. At a subthalamic hypothyrosis reaction on is raised, and its peak often moves by 60th minute. The reaction delay, however, is observed sometimes at patients with a pituitary body lesion. Reaction disturbance meets at patients chronic renal insufficiency. Risk. In the course of assay carrying out there are no essential dangers. Right after injections there is a caumesthesia, a nausea, strange taste in a mouth and a desire to an emiction that proceeds during 30-60 with, and then disappears. LUTEINIZING AND FOLLICLE-STIMULATING HORMONES Definition of initial level Results of definition and vary depending on techniques and the standards used in different laboratories. The majority of the published value is received at use of the second MPS/MGCH. Level at women makes approximately 4-15 honey/ml in and phases, 10-50 honey/ml in the middle of a cycle and 30-200 honey/ml after menopause offensive. Level is peer 4-30 mmed/ml in a phase, 30-150 honey/ml in the middle of a cycle, 4 40 honey/ml in a phase and more 40 honey/ml after menopause vpxl offensive. At men about 60-70 years level of these hormones are elderly is similar to that at women in a phase; later it is enlarged. Though low level cannot be distinguished from normal, absence of rising of maintenance or at patients with clinical or biochemical signs of a hypogonadism specifies in a hypothalamus or pituitary body hypofunction. assays Assay with a rilizing-hormone of a luteinizing hormone (Lg - Rg-or the Gnrg-test). Now in the USA it is accessible only as an agent to research. Technique. Intravenously enter 100 mkg ; blood samples for definition and take on 0, 15, 30 and 60th minute-ambassador of introduction. Not changed indicators. Indicators of not changed reaction in different laboratories considerably differ from each other. As a rule, for norm accept rising of level more than on 12 mmed/ml, and more than on 3 mmed/ml at women and more than on 8 mmed/ml, and more than on 3 mmed/ml at men. At women reaction depends on a stage of a menstrual cycle, and the maximum reaction is observed in the middle of it. Maximum value are registered during the first 30 mines, but concerning at some persons. These value can be observed later. Interpreting of results. At patients with a reaction hypopituitarism on can be within norm. Are lowered or even completely to be absent, and it is fair and concerning patients with subthalamic disorders. If not changed reaction allows to exclude a hypogonadism aetiology the lowered reaction or its absence speaks nothing about anatomic localisation of disturbance. Nevertheless results of the test reflect functional ability ; if pituitary body function in other relations is not broken, the lowered reaction specifies in absence of influence endogenous . Deficiency of estrogens usually reduces reaction in larger degree, rather than reaction , causing a distortion of the relation of reactions FSG/LG. At women with a secondary amenorrhea of a subthalamic parentage (for example, at a nervous anorexia) reaction can be strengthened. Assay with .