At check of endocrine function

At check of endocrine function at the majority of patients with a syndrome of initially "empty" Turkish saddle receive results though there are reports on depression at some sick reserves and Gonadotropinums, an obtusion of reaction of a hormone of growth and sometimes a panhypopituitarism or . The diagnosis of a skelaxin syndrome of initially "empty" Turkish saddle establish usually in the course of inspection about definition of a tumour of a pituitary body. Possibility of this syndrome should be assumed at the patient with the enlarged sizes of a Turkish saddle in the absence of clinical semiology (or minimal - The cases described within 1977 (on Jordan and co-workers. [101] in updating) ache its expressions) and not changed endocrine function. In these conditions often there is no necessity for carrying out of a pneumoencephalography and it is necessary to observe of the patient simply. It is important to remember, however, that the "empty" Turkish saddle does not exclude simultaneous existence of a tumour of a pituitary body. At patients with a syndrome of initially "empty" Turkish saddle were STG - prolaktin - and AkTg-sekretirujushchie tumours [100, 132, 139]. However, problems of diagnostics at such patients are defined by signs of a hypersecretion of hormones, and a syndrome of an "empty" Turkish saddle if it is diagnosed before operation, does not influence a treatment planning.
Till now cases of simultaneous existence of a nonfunctioning tumour of a pituitary body and a syndrome of a primary "empty" Turkish saddle are not described. diseases Many and various disturbances arising in of area, are accompanied by signs and symptoms which imitate pituitary body tumours. Such disturbances concern inflammatory and diseases (a sarcoidosis, an eosinophilic granuloma, an arachnoiditis), degenerate processes (aneurysms) and neoplasms (meningiomas, , sarcomas, and sometimes metastasises of other tumours). Extending on a Turkish saddle, these processes can cause its expansion and deformation of osteal structure and, besides them implications, can be accompanied by this or that degree of a hypopituitarism. For a choice of their correct treatment it is necessary to distinguish from primary tumours of a pituitary body. At tumours usually observe development of mainly neurologic symptoms: the serious headache often accompanied by a nausea and vomiting, azygomorphous disturbances robaxin of fields of vision, an optic nerve and lesion edema nerves. Tumours of a hypothalamus or walls of III ventricle often cause symptoms of dysfunction of a hypothalamus and rising of intracranial pressure. Unlike pituitary body tumours in these cases endocrine implications usually appear later, instead of before neurologic symptoms. The X-ray inspection often promotes parentage finding-out tumours when find out, for example, a calcareous infiltration at cranyopharyngiomas and meningiomas and erosion of the forward rejected processes in the rest of an intact Turkish saddle. A usual method of revealing tumours is the pneumoencephalography though many of these tumours are easily identified by means of Kt-scanning. Aneurysms of a siphon of an internal carotid or forward arteries can extend on a Turkish saddle and similarly to tumours imitate a tumour of a pituitary body [140]. A prevailing symptom is the headache of often pulsing character and varying acuteness; also the lesion III, IV and VI pairs cranial nerves is often observed. Before operation the diagnosis can be established only by means of an angiography of carotids. Sarcoidosis and others diseases initially amaze a hypothalamus, and the mechanism with which help they cause augmentation of the sizes of a Turkish saddle, is found out not completely. The diagnosis put usually on the basis of not endocrine implications, and the assumption of secondariness it is necessary for pathology to confirm with reaction to corresponding treatment and results long observations. Augmentation of the sizes of a pituitary body at other endocrine diseases The long primary hypothyrosis or primary hypogonadism is accompanied by expansion of a Turkish saddle, augmentation of secretion or Gonadotropinums and at some tumours of a pituitary body sick of development TtG-sekretirujushchih [8-10, 141]. As it is possible to show on laboratory animals, long insufficiency of function of a peripheric gland leads to a hyperplasia of the cells cosecreting corresponding a hormone and eventually to development of a tumour. Sometimes at insufficiency of function of one of peripheric glands the hypersecretion not only corresponding, but also others pituitary body hormones that observe at long a hypothyrosis which is accompanied by premature puberty is shown.