Dofaminum does not lead to acute

Dofaminum does not lead to acute depression of level of a hormone that testifies to defect in [88]. These shifts, no less than , remain at a hemodialysis, but disappear after kidney transplantation. Rising of level of Prolactinum in 2-3 times was observed at a cirrhosis, especially at patients with a hepatic encephalopathy [205]; it consider as result buy tegretol of formation false which role is suspected and of other implications of disease from party TSNS. Prolactinum production observed in cancer tumours of lungs and kidneys [205] though ectopic secretion of this hormone nevertheless is rather rare. The galactorrhea and can be registered after damages of a spinal cord and thorax walls (combustions, the cuts, surrounding deprive) when 4-6th intercostal nerves which stimulation causes out of-patrimonial a lactemia [206 are involved in process, 207]. Anaesthesia of intercostal nerves reduces level of Prolactinum and often lactemia [207]. In the absence of all these disturbances, and also anamnestic indicatings on reception of corresponding medicinal preparations of the patient at which Prolactinum level in plasma is raised and there are no changes in area of a Turkish saddle on the tomogram, represents a difficult diagnostic problem. To the description of such condition apply the term idiopathic , but to differentiate "functional" disturbance of secretion of
Prolactinum and hidden a tumour hardly. and-or a galactorrhea are often observed at women with safety of a menstrual cycle or with an amenorrhea after the termination of reception of peroral contraceptives or during the long period after sorts. Some of these women eventually have anatomic signs of a tumour of a pituitary body whereas at others this condition remains throughout many years or normal secretion of Prolactinum is restored. As pituitary body tumours can be found at women with the anamnesis of a galactorrhea within 20 years (irrespective of disturbances of a menstrual cycle), it is not excluded, that the majority of patients with idiopathic has such tumours, but too small size that they could be found out. Results of dynamic researches of secretion of Prolactinum at these patients, similar to those at patients with pituitary body tumours [193, 203], confirm such possibility. Extreme importance is got by continuous observation over these patients with periodic a tomography of a Turkish saddle and Prolactinum definition in plasma. At patients with a galactorrhea, but normal level of Prolactinum, at dynamic researches of its secretion usually receive normal results; the probability of a tumour of a pituitary body at them is small and it is possible to prognosticate conservation of ovulatory menstrual cycles and a fecundity. At this group of persons it becomes perceptible, possibly, most widespread type a galactorrhea caused, apparently, by a hypersensibility of mammary glands to normal level of Prolactinum buy zanaflex in plasma. Usually this form of a galactorrhea is shown by conservation of a postnatal lactemia or arises after the termination of reception of peroral contraceptives. Pathogenesis tumours a hypothalamus or pituitary body pathology It is standard, that in a basis , appearing after cancellation of peroral contraceptives or remaining during excessive term after sorts dysfunction (hypothalamus), most likely, lays. Idiopathic also consider as result of disturbance gipotalamo-gipofizarnyh mechanisms [208]. Disagreements exist of, whether this disturbance by the intermediate condition eventually leading to formation of an adenoma is, and whether defect systems in subthalamic areas or on receptors ( 7-17) is localised. In favour of a subthalamic parentage following data testify: 1 - antagonists receptors (for example, aminazine), breaking transfer in and raising level of Prolactinum at healthy people, at patients with tumours are noneffective, that specifies in absence or reduction endogenous a tonus [127, 203]; 2-disturbance of reaction of Prolactinum on , characteristic for patients with tumours, it is possible to reproduce and at healthy faces by preliminary introduction of the antagonist by it receptors (Metoclopramidum) [209] that specifies in necessity a tonus for normal reaction of Prolactinum and to other stimulus; 3 - secretion of Prolactinum by a tumour, as a rule, can be braked by infusion of Dofaminum, which dejst - it is immediate on a pituitary body, or L- which both on periphery, and in turns to Dofaminum. However if with the help in the doses which are not getting through a hematoencephalic barrier to brake peripheric decarboxylation L- ceases to oppress Prolactinum secretion though at healthy faces in similar conditions its brake effect remains; 4 - introduction to healthy faces reduces levels of Dofaminum,