воскресенье, 21 декабря 2008 г.

Apparently, the majority

Apparently, the majority of tumours grows on an average line of an upper edge of a leg of a pituitary body though some originate in more-low departments of a leg, and about 15 grasp the top part / of a forward share of a pituitary body and consequently settle down in borders of a Turkish saddle. Large tumours shift upwards an optic chiasm, and also displace a hypothalamus and III ventricle. From below the tumour can squeeze a forward order levitra share of a pituitary body, but leads to an atrophy of a back share owing to leg damage is more often. Usually consider, that the tumour occurs from the pocket rests , however it is doubtful, as it is infrequently localised in a saddle and seldom settles down along the embryonal tract which is passing through a bone. SIGNS AND SYMPTOMS Initial implications of tumours of a pituitary body, no less than their subsequent symptoms, it is possible to part on three basic groups , radiological and endocrine. Not endocrine semiology inherent to all tumours of a pituitary body is more low surveyed mainly; features separate tumours will be surveyed separately. For last two decades as perfection of methods researches and an estimation of hormonal function of a pituitary body caused possibility of more and more early statement of the diagnosis and the treatment beginning, frequency distribution of symptoms of tumours of a pituitary body has considerably changed.
For example, if from the big number of patients with the tumours of a pituitary body diagnosed in 1940-1950, almost 90 had disturbances of sight [124] among recently surveyed patients such disturbances met only in 25 of cases [126, 127]. It is possible to expect, that this percent will decrease and further. And on the contrary, now most common symptoms are disturbances of endocrine function, more often an amenorrhea, depression or the sterility, bound with tumours whereas, according to former observations, such semiology was available all for 25-35 of patients. Both earlier, and now on a share casually found out at roentgenography of a skull of tumours of a pituitary body had and it is necessary small percent of cases. Nejroanatomichesky implications The augmentation of the sizes to a tumour leads to a compression surrounding to a tissue and pressure upon a firm cerebral cover laying from above which forms a diaphragm of a Turkish saddle. It in turn causes the headache of various character localised in frontal, temporal or of area, usually stupid, not accompanied by a nausea or symptoms of disturbance of the sight, not dependent on position of a body and not always taken out by analgetics. At rupture of a firm cerebral cover the headache often stops. Having started to grow upwards, the tumour meets optic nerves, a visual decussation or visual tracts on the way. More often the tumour decadron puts pressure upon a visual decussation, leading to occurrence of classical signs of a bitemporal hemianopsia. At inspection of the patient in the earliest terms of a prelum of an optic chiasm it is possible to find defects only a field of vision, and azygomorphous changes are often observed. With continuation of growth of a tumour the loss of sight can progress to full blindness and eventually the atrophy of optic nerves will develop. Sometimes the tumour grows mainly to front from a visual decussation, leading to sight disturbance only in one eye. The papilledema at pituitary body adenomas meets seldom, but at cranyopharyngiomas he can be found out in 27 of patients [125]. In process of the further growth of a tumour upwards there can be symptoms of a prelum of a ventral hypothalamus that is shown in body temperature fluctuations, , change of character of a dream and emotional shifts. At pressure upon III ventricle there can be an internal hydrocephaly. In rare instances there is a prelum of frontal or temporal shares of a brain that is accompanied by behavioural disturbances and attacks; it is possible to observe also lesion signs the ways, testifying to a mesencephalon prelum. The prelum of extrahypothalamic structures occurs at cranyopharyngiomas which can be localised out of a Turkish saddle, than at pituitary body adenomas is more often. Tumour growth in a direction can lead to a prelum III, IV and VI pairs cranial nerves in a place where they pass through a cavernous sine that causes an ophthalmoplegia and a diplopia. Tumour growth downwards leads to rupture of a bottom of a Turkish saddle and process diffusion on a clivus or sinuses of the basic bone that can cause the efflux from a nose of a spinal liquid (). Though usually the tumour grows slowly and symptoms progress gradually, at patients with tumours the semiology can suddenly appear, that is bound to a hemorrhage in a tumour, or an apoplexy of a pituitary body [95].

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