They also similarly

They also similarly stimulate a lipolysis. Thus, concentration of a glucose in blood raises at the expense of pauperisation by substrate of some tissues. However the glucose becomes accessible to immediate use by other tissues and in particular a brain which conservation of functions has crucial importance for a survival and depends on substrate; this tissue is not a target of catabolic action of glucocorticoids. ANTAGONISM OF HORMONES: MORE THIN REGULATION OF THE METABOLISM In many cases reactions to influence order buy ultram of hormones are resisted by reactions to influence of other hormone (hormones). It frames additional possibility of the termination or reduction of intensity of reaction and more thin regulation of a metabolism. Insulin counteracts raising level of a glucose to influences of adrenaline, a glucagon, glucocorticoids, a-adrenergic agonists and . It stimulates glucose absorption, and also Adeps and glycogen synthesis. Simultaneously it brakes glucose synthesis, a lipolysis and a glycogenolysis. It is besides, juvenile stimulates synthesis of fiber and inhibits its disintegration. Progesterone blocks some effects of estrogens. reduces level 2 + in blood serum whereas the parathyroid hormone () raises it. In some cases the antagonism is shown not in every respect. For example, though effects of insulin in the majority are opposite to effects of glucocorticoids, action of both hormones is referred on intensifying of accumulation of a glycogen.
As and-. And b-adrenergic agonists stimulate a glycogenolysis and [4] though two classes of these hormones can make opposite impact on vascular, muscular and hormonal (for example, insulin secretion) reactions. The reason, on which hormones of two different classes can be synergists in one relations and antagonists in others though it is not always obvious, but can be understood from positions of already analysed possible evolution of plural communications between symbols and domains of reactions. REGULATION OF PRODUCTION OF HORMONES In general a major factor regulating level of a hormone in blood, rate of its entering in a blood flow is. This process is supervised by the influences capable quickly to change rate of secretion of a hormone and (usually more slowly) rate of its biosynthesis. Further, buy vpxl scam at longer stimulation there can be a hypertrophy and-or a hyperplasia of an endocrine gland. In some cases hormone production is supervised basically by the substrate which level is regulated by this hormone. For example, insulin entering in blood is rigidly bound to concentration of a glucose in plasma, and secretion - with level 2 + in it. Concerning other hormones it not so. Production of steroid and thyroid hormones is regulated by level corresponding hormones (, , , ), production and which secretion (except for ) is supervised through subthalamic rilizing-hormones. In most cases one can influence hormone production not, and some stimulus though any of them the role of the main regulating factor belongs. For example, though production has the circadian character defined by supervising action , many stimulus of a various sort (a shock, a hypoglycaemia, sharp excitation) can interfere with this process (at least through the same ) and to raise production a hormone. Like it though insulin production is regulated mainly by glucose level in blood, sympathetic activity or amino acids containing in blood also can make on its impact. In many cases hormones or their effects appear the stimulus braking by a principle of a feedback own production. Glucocorticoids and 3 inhibit accordingly production and . Depression of level of a glucose under the influence of insulin oppresses insulin secretion. Rising of level 2 + under the influence of brakes secretion of this hormone. The listed kinds of influences taken as a whole allow to support co-ordination hormonal production at certain level (for example, in an initial condition) and provide possibility of reaction of endocrine system on other stimulus when it appears useful to refuse usual regulation of a homeostasis. DEFINITION OF THE CLASS OF HORMONES As a rule, hormones classify according to their metabolic effects. Though such classification is represented rather simple, in practice it meets certain difficulties. The hydrocortisone, for example, in physiological concentration can possess the same influence on a saline exchange, as Aldosteronum or a cortexone. Whether it is necessary to consider as glucocorticoid action? Insulin in high concentration can cause the same effect, as [6]. Whether to consider this action insulinoid or ? The explanation of it is reduced to that insulin at its sufficient concentration can contact a receptor and by that to operate through this receptor, and the hydrocortisone can be bound and operate through a receptor mediating effect of Aldosteronum [4, 6]. In these positions the way of an estimation of hormonal effects and their classification by character of receptors which mediate certain reactions [4] disappears. Actually such way of classification of hormonal effects for a long time already use in pharmacology. For example, effects of catecholamins classify or as a - or as b-adrenergic, and b-adrenergic section on b1 - and b2-effects further. Thus, the receptors mediating hormonal influences, it is possible to characterise, proceeding from immediate research of their binding ability and character of the reactions which are growing out of linkage with them of hormones. In endocrinology receptors usually are called under the name of the basic hormone or a class of the hormones which are carrying out through them the action (insulinic, androgenic receptors, receptors , etc.).